AAV Transduction Database (SPIRIT)

Graphs below depict the results of transduction of different cultured cell types with various recombinant Adeno-associated virus (AAV) vectors encoding a yellow fluorescent reporter. The vectors were either based on wild-type AAV serotypes or on capsid variants that were derived from the wild-types through insertion of distinct peptides (one peptide variant per capsid). In the bubble charts, transduction rates (i.e., percent of fluorescent reporter-positive cells) are illustrated by the circle radius/area, and the expression strength (i.e., median fluorescence signal) is indicated by the color (black: low > green: high).

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